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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ETFDH
All Species:
37.88
Human Site:
T419
Identified Species:
59.52
UniProt:
Q16134
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16134
NP_004444.2
617
68495
T419
E
S
I
F
N
Q
L
T
S
E
N
L
Q
S
K
Chimpanzee
Pan troglodytes
XP_517508
617
68419
T419
E
S
I
F
N
Q
L
T
S
E
N
L
Q
S
K
Rhesus Macaque
Macaca mulatta
XP_001097120
616
68420
T419
E
S
I
F
N
Q
L
T
S
E
N
L
Q
S
K
Dog
Lupus familis
XP_853781
600
66768
T402
E
S
I
F
K
Q
L
T
S
E
N
L
Q
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q921G7
616
68072
T418
E
S
I
F
K
Q
L
T
S
E
N
L
Q
S
K
Rat
Rattus norvegicus
Q6UPE1
616
68180
T418
E
A
I
F
K
Q
L
T
S
E
N
L
Q
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510390
669
74482
T471
D
A
I
F
N
Q
L
T
T
E
N
L
Q
S
K
Chicken
Gallus gallus
NP_001026705
477
53116
G291
D
E
K
K
W
K
P
G
R
V
E
H
T
V
G
Frog
Xenopus laevis
NP_001087869
616
68418
T418
E
T
I
F
K
Q
L
T
D
E
N
I
Q
S
K
Zebra Danio
Brachydanio rerio
NP_001004598
617
68912
T419
E
T
A
F
S
K
I
T
D
E
N
L
Q
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610536
604
65970
E406
L
A
A
E
S
A
F
E
A
I
N
A
D
A
Q
Honey Bee
Apis mellifera
XP_624722
606
67014
I408
E
S
I
I
E
A
L
I
D
A
E
N
N
P
S
Nematode Worm
Caenorhab. elegans
Q11190
597
65317
D398
A
A
E
S
I
F
E
D
I
Q
Q
K
G
E
D
Sea Urchin
Strong. purpuratus
XP_792035
613
67384
T415
E
A
I
Y
D
R
L
T
Q
E
D
A
S
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08822
631
69615
K416
E
S
I
F
E
S
I
K
G
L
P
V
L
E
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.8
92.2
N.A.
92.3
93.1
N.A.
82
65.4
84.2
80.8
N.A.
65.1
67.7
59.9
70
Protein Similarity:
100
99.6
99
94.6
N.A.
95.7
95.9
N.A.
88.4
70.6
91.9
90.5
N.A.
78.9
80.8
75.6
81.8
P-Site Identity:
100
100
100
93.3
N.A.
93.3
86.6
N.A.
80
0
73.3
53.3
N.A.
6.6
26.6
0
40
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
100
13.3
86.6
86.6
N.A.
40
26.6
13.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
49.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
64.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
34
14
0
0
14
0
0
7
7
0
14
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
14
0
0
0
7
0
0
7
20
0
7
0
7
0
7
% D
% Glu:
74
7
7
7
14
0
7
7
0
67
14
0
0
14
14
% E
% Phe:
0
0
0
67
0
7
7
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
7
7
0
0
0
7
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
0
0
74
7
7
0
14
7
7
7
0
7
0
0
0
% I
% Lys:
0
0
7
7
27
14
0
7
0
0
0
7
0
0
54
% K
% Leu:
7
0
0
0
0
0
67
0
0
7
0
54
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
27
0
0
0
0
0
67
7
7
0
0
% N
% Pro:
0
0
0
0
0
0
7
0
0
0
7
0
0
7
0
% P
% Gln:
0
0
0
0
0
54
0
0
7
7
7
0
60
0
14
% Q
% Arg:
0
0
0
0
0
7
0
0
7
0
0
0
0
0
0
% R
% Ser:
0
47
0
7
14
7
0
0
40
0
0
0
7
67
7
% S
% Thr:
0
14
0
0
0
0
0
67
7
0
0
0
7
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
7
0
7
0
7
0
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _